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Conflict of interest The authors declare no competing interests

Public RNA-seq and proteomic datasets for FunMap analyses External datasets included BeatAML (707 samples), TCGA-AML (173 samples, cBioPortal), TARGET-AML (2,762 AML, 442 normal, 18 cell lines, GDC), Clinseq-AML (274 participants, Wang et al.), Blood2022 proteomics (44 participants, Kramer et al.) and DepMap 22Q2 cell line RNA-seq

This ongoing oxidative stress leaves endothelial cells (the lining of blood vessels) highly vulnerable to ongoing damage, contributing to the micro-clotting and "immunothrombosis" frequently observed in Long Haulers

Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb

1996, 270 (2 Pt 1): E209-E214